AVN-397

AVN-397 is a 5-hydroxytryptamine subtype 6 receptor antagonist drug developed by Avineuro Pharmaceuticals Inc. that can potentially be used to treat Alzheimer's disease and general anxiety disorder (GAD).[1][2] Avineuro announced that it would start Phase II clinical trials in 2009, and those trials are ongoing as of 2012.[3][4][5]

References
  1. Griebel, Guy; Holmes, Andrew (2013). "50 years of hurdles and hope in anxiolytic drug discovery". Nature Reviews Drug Discovery. 12 (9): 667–687. doi:10.1038/nrd4075. ISSN 1474-1776. PMC 4176700. PMID 23989795. S2CID 6531810.
  2. "AVN 397 - AdisInsight". adisinsight.springer.com. Retrieved 2023-03-12.
  3. "Avineuro Announces Beginning Of Phase II Clinical Studies Of AVN-397, Potent Small Molecule For Treatment Of Anxiety And Alzheimer's Disease". BioSpace. Retrieved 2023-03-12.
  4. "Cognitive enhancers (Nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. Disease-modifying drugs. Update 2014". docksci.com. S2CID 998047. Retrieved 2023-03-12.
  5. Medicines in Development / Mental Illnesses / 2012 Report (PDF), archived (PDF) from the original on 9 Jul 2022
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