BNR/Asp-box repeat

BNR/Asp-box repeat is a repetitive sequence of amino acids contained in some proteins.

BNR/Asp-box repeat
Structure of a bacterial sialidase.[1]
Identifiers
SymbolBNR
PfamPF02012
Pfam clanCL0434
InterProIPR002860
SCOP21euu / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes. The repeats are short, however the repeats are never found closer than 40 residues together suggesting that the repeat is structurally longer. These repeats are found in a variety of non-homologous proteins, including bacterial ribonucleases, sulphite oxidases, reelin, netrins, sialidases, neuraminidases, some lipoprotein receptors, and a variety of glycosyl hydrolases.[2]

Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes.


Examples

Human genes encoding proteins containing this domain include:

References
  1. Gaskell A, Crennell S, Taylor G (November 1995). "The three domains of a bacterial sialidase: a beta-propeller, an immunoglobulin module and a galactose-binding jelly-roll". Structure. 3 (11): 1197–205. doi:10.1016/s0969-2126(01)00255-6. PMID 8591030.
  2. Copley RR, Russell RB, Ponting CP (February 2001). "Sialidase-like Asp-boxes: sequence-similar structures within different protein folds". Protein Science. 10 (2): 285–92. doi:10.1110/ps.31901. PMC 2373934. PMID 11266614.
This article incorporates text from the public domain Pfam and InterPro: IPR002860
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.