IIE
IIE may stand for:
- The Independent Institute of Education, South Africa
- Innovative Interstellar Explorer, a proposed mission to send a probe to the heliopause
- Institut d'Informatique d'Entreprise, French public Grandes écoles specializing in computer science
- Institute for International Economics, economics think tank based in Washington, D.C.
- Institute of Industrial Engineers, world's largest professional society for industrial engineering professionals
- Institute of International Education, a world leader in the international exchange of people and ideas
- Institution of Incorporated Engineers, once the UK's largest multidisciplinary engineering association, now part of IET
- Instituto de Investigaciones Estéticas, art history research institute at Mexico's National Autonomous University (UNAM)
- The Apple IIe, the third model in Apple's line of Apple II computers
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