Melrose

• Melrose, Scottish Borders, a town in the Scottish Borders, Scotland
  • Melrose Abbey, ruined monastery
  • Melrose RFC, rugby club

• Melrose, Queensland, a locality in the South Burnett Region
• Melrose, Queensland (Southern Downs Region), a neighbourhood in Killarney
• Melrose, South Australia, a town in the southern Flinders Ranges
• Melrose, Tasmania, a locality in the North-West Region
• Melrose Park, South Australia, a suburb of Adelaide

• Melrose, Hastings County, Ontario, a community in the township of Tyendinaga
• Melrose, Middlesex County, Ontario, a community in the township of Middlesex Centre
• Melrose, Nova Scotia
• Melrose, New Brunswick
• Melrose, Newfoundland and Labrador
• Melrose, Nova Scotia

• Melrose, Mauritius, a village in Mauritius

• Melrose, New Zealand, a suburb in the Eastern Ward of Wellington City

• Melrose, Gauteng, a suburb of Johannesburg
• Melrose Estate, Gauteng, a suburb of Johannesburg
• Melrose House, historic mansion in Pretoria
• Melrose North, Gauteng, a suburb of Johannesburg

• Melrose Avenue, a major street running through Los Angeles and West Hollywood, California
• Melrose District, a neighborhood in Phoenix, Arizona on the border of the Encanto and Alhambra urban villages.
• Melrose, Oakland, California
• Melrose, California, former name of Cherokee, Nevada County, California
• Melrose, Connecticut, a village in East Windsor
• Melrose, Florida, an unincorporated town
• Melrose, Iowa, a city
• Melrose, Louisiana, a village
  • Melrose Plantation, a plantation in Natchitoches, Louisiana
• Melrose, Maryland, an unincorporated community
• Melrose, Massachusetts, a city located in the Greater Boston metropolitan area
• Melrose, Minnesota, a city
• Melrose, New Jersey, an unincorporated community
• Melrose, New Mexico, a village
• Melrose, New York, a hamlet of the Town of Schaghticoke
• Melrose, Bronx, a residential neighborhood in the New York City borough of the Bronx
  • Melrose (Metro-North station)
• Melrose, Ohio, a village
• Melrose-Rugby, Roanoke, Virginia, a neighborhood in central Roanoke
• Melrose, Wisconsin, a village
• Melrose (town), Wisconsin, a town
• Melrose Township (disambiguation)

Registered historic places:

• Melrose (Danville, Kentucky) in listed on the NRHP in Boyle County, Kentucky
• Melrose (Natchez, Mississippi), a mansion in Natchez National Historical Park
• Melrose (Murfreesboro, North Carolina) in listed on the NRHP in Hertford County, North Carolina
• Melrose (Cheyney, Pennsylvania) in Cheyney, Pennsylvania
• Melrose (Casanova, Virginia), listed on the NRHP in Fauquier County, Virginia
• Melrose (Fork Union, Virginia), listed on the NRHP in Fluvanna County, Virginia