National Firefighter Registry

The National Firefighter Registry (NFR) is a voluntary registry of firefighters in the United States used to collect relevant occupational, lifestyle, and health information on firefighters for evaluating cancer rates and cancer risk factors in the U.S. fire service. It aims to use this data to reduce cancer in firefighters. The NFR was created by the Firefighter Cancer Registry Act of 2018 in response to growing evidence of carcinogenic exposures and increased risk for cancer faced by firefighters.[1] It is expected to begin registering firefighters in 2022. The NFR is maintained by the U.S. National Institute for Occupational Safety and Health (NIOSH).

National Firefighter Registry
Program overview
FormedJuly 7, 2018 (2018-07-07)
Parent agencyU.S. National Institute for Occupational Safety and Health
Websitehttps://www.cdc.gov/NFR

Cancer among firefighters

A firefighter exits a burning building
Firefighter using a water hose on fire truck to extinguish a portion of a forest fire
A firefighter moving through a bush fire

Cancer risk in the U.S. fire service is a topic of growing concern. Recent studies suggest that exposure on the fireground may increase risk to firefighters of certain types of cancer and other chronic diseases.[2][3][4][5][6][7][8][9][10][11] Major international studies generally support findings from U.S. studies that firefighters experience increased rates of cancer, with some variation by cancer site.[12][13][14][15][16][17][18][19][20]

Firefighters regularly encounter carcinogenic materials and hazardous contaminants, which is thought to contribute to their excess cancer risk. Dozens of chemicals classified by the International Agency for Research on Cancer (IARC) as known or probable carcinogens have been identified on the fireground.[1][21] Several studies have documented airborne and/or dermal exposures to carcinogenic compounds during firefighting, as well as contamination on turnout gear and other equipment worn by firefighters.[22][23][24][25][26]  Some of these compounds have been shown to absorb into firefighters’ bodies.[27][28]

In addition to chemical exposures, firefighters also often work 24-hour or longer shifts; they also respond to emergencies and work shifts at night. Night shift work has been classified by IARC as a probable human carcinogen factor.[29] Some firefighters also work with hazardous materials and are trained to control and clean up dangerous materials such as oil spills and chemical accidents. As firefighters combat a fire and clean up hazardous materials, they risk harmful chemicals contacting their skin or penetrating their personal protective equipment (PPE).[20] In June 2022, IARC classified occupational exposure as a firefighter as “carcinogenic to humans.”[30]

There are many types of firefighters. Most research on firefighters’ cancer risk has involved structural or municipal career firefighters. Wildland firefighters are specially trained firefighters tasked with controlling forest fires. They frequently create fire lines, which are swathes of cut-down trees and dug-up grass placed in the path of the fire. This is designed to deprive the fire of fuel. Wildland firefighting is a physically demanding job with many acute hazards. Wildland firefighters may hike several miles while carrying heavy equipment during the wildfire season, which has increased in duration over time, especially in the western United States. Unlike structural firefighters, wildland firefighters typically do not wear respiratory protection, and may inhale particulate and other compounds emitted by the wildfires. They also use prescribed fires to burn potential fire fuel under controlled conditions.[31] To examine cancer risk for wildland firefighters, a risk assessment was conducted using an exposure-response relationship for risk of lung cancer mortality and measured particulate matter exposure from smoke at wildfires. This study concluded that wildland firefighters could have an increased risk of lung cancer mortality.[32] When not on the scene of an emergency, firefighters remain on call at fire stations, where they eat, sleep, and perform other duties during their shifts. Hence, sleep disruption is another occupational hazard that they may encounter at their job.[25]

The research on cancer for other subspecialty groups of firefighters is limited, but a recent study of fire instructors in Australia found an exposure-response relationship between training exposures and cancer incidence.[33]

In addition to epidemiological studies, mechanistic studies have used biomarkers to investigate exposures' effects on biological changes that could be related to cancer development. Several of these studies have found evidence of DNA damage, oxidative stress, and epigenetic changes related to firefighters' exposures.[34][35][36][37][38][39][40]

History

Background

Due to the lack of central and comprehensive sources of data, research on cancer rates amongst firefighters has been challenging. Although some evidence suggests the risk for specific cancer types could vary for male, female, and non-white firefighters,[41][42][43][44] the strength of the evidence related to cancer in demographic subgroups is limited because many previous studies have mainly comprised white male samples of firefighters. Larger samples of female firefighters and minority groups are needed before the conclusions can be drawn about cancer risk across the nation’s diverse fire service.[45][46]

Additionally, while state cancer registries provide rich data for studying cancer in the U.S., state cancer registries often do not provide comprehensive information on cancer patients’ work history[47][48][49] and workplace practices, making it challenging to use this data source alone for studying cancer in firefighters. It is also important to collect information on personal and lifestyle risk factors (e.g. tobacco and alcohol use, sleep deprivation, diet, and physical activity) in the U.S. fire service to better understand how they may affect the relationship between firefighting and cancer.[50][51][52]

Creation and implementation

Firefighter Cancer Registry Act of 2018
Long titleAn Act to require the Secretary of Health and Human Services to develop a voluntary registry to collect data on cancer incidence among firefighters
Enacted bythe 115th United States Congress
Citations
Public lawPub. L. 115–194 (text) (PDF)
Codification
U.S.C. sections created42 U.S.C. § 280e-5
Legislative history

The Firefighter Cancer Registry Act of 2018 bill was introduced in the U.S. House of Representatives on February 7, 2017, by Robert Menendez.[53][54] It required the Centers for Disease Control and Prevention to create a registry designed to collect data on cancer rates among U.S. firefighters.[55][56][57] The bill was passed with unanimous and bipartisan approval.[58][59][60][61] On July 7, 2018, Congress passed the bill, mandating CDC to create a National Firefighter Registry (NFR).[62] The Congressional Budget Office estimated that the bill would cost around 10 million dollars.[62][63] However, the Republican Policy Committee states that the cost of the bill would be offset by a reduction in the funding of the CDC.[64]

NIOSH, part of the CDC, has been given authority to lead this effort (beginning in fiscal year 2019) with input from the scientific and firefighting communities.[62] The NFR program receives input and guidance from the NFR Subcommittee, a subcommittee of the NIOSH Board of Scientific Counselors (a Federal Advisory Committee), consisting of 12 rotating subject matter experts in firefighting, epidemiology, medicine, or public health.[65][66] The CDC and NIOSH expect the NFR to be open for enrollment in the Fall of 2022.[62][67]

Operation

The proposed approach for the NFR states it will be a "surveillance system" of U.S. firefighters over the age of 18 years. The main goal of the NFR, according to the text of the law, is "to develop and maintain…a voluntary registry of firefighters to collect relevant health and occupational information of such firefighters for purposes of determining cancer incidence."[68][69] According to the Republican Policy Committee's summary, the NFR aims to provide decision makers with data to help them create new protocols to protect firefighters.[62] It aims to register around 200,000 firefighters across a variety of demographics within 5 years.[68] NIOSH plans to recruit firefighters through various communication channels (e.g., NFR website and newsletter, social media, local/state/national unions, affinity groups, trade journals, conference attendees) or directly from selected rosters of firefighters.[68][70]

Participation in the NFR is entirely voluntary and is open to all firefighters, including retired ones. Firefighters who register will provide their name, date of birth, and information about their lifestyle and exposures. Following this participants may be given voluntary yearly questionnaires.[70] NIOSH can then use this information to track past and future diagnoses of cancer among NFR participants by matching with data from state cancer registries to understand how firefighters’ work impacts their risk of developing cancer.[68][70]

Cancer is a nationally notifiable condition, and thus all U.S. states track diagnoses of cancer in a state cancer registry.[71] The NFR is planned to also seek additional details about participant’s types of emergency responses attended and exposures by working with fire departments and exposure tracking programs (if applicable), and by administering follow-up questionnaires to registered firefighters. Because cancer has a long latency period – which is the time between exposure to carcinogens and the development of cancer – the NFR will monitor cancer outcomes for decades.[68][70]

Firefighter enrollment

According to NIOSH's website all members will enroll through a web portal. Their website also states that any information gathered through the program will only be accessible to NIOSH researchers and will be protected with multi-factor authentication and "multiple layers of encryption."[70] Firefighters may access the web portal through the dedicated NFR website (https://www.cdc.gov/niosh/firefighters/registry.html or https://www.cdc.gov/NFR) or by directly accessing the web portal when it launches. To complete enrollment in the NFR, participants will need to set up an account, complete an informed consent document, user profile, and enrollment questionnaire.[68][70]

The user profile will serve to collect basic information from the firefighter that could change over time and hence can be accessed and updated by the user. The enrollment questionnaire will collect information on employment/workplace characteristics, exposure, demographics, lifestyle factors, comorbidities, and other confounders. The enrollment process, including the questionnaire, is designed to take 30–45 minutes to complete.[68][70] Following enrollment, NIOSH will send NFR participants notifications for periodic follow-up questionnaires (e.g., one per year) to be filled out through the web portal.[68][70]

Other sources of information

In addition to roster information, NIOSH plans to request fire incident records dating back to January 1, 2010, or earlier when available, from fire departments for some participants. Fire departments are required to collect some basic information about fire incidents under the National Fire Incident Reporting System (NFIRS) established by the U.S. Fire Administration. Department incident records will provide NIOSH investigators with apparatus and incident-specific information to be used as surrogates of exposure for exposure-response analyzes. Specific variables of interest requested from department incident records may include: incident number, fire station, apparatus, incident type (structure fire, car fire, etc.), on scene time, off scene time, job assignments, number of fire runs, and duration at fires. NIOSH will explore obtaining records directly through states, NFIRS, and/or software vendors to reduce the burden on each participating fire department.[68][70]

References

  1. Marques, M Matilde; Berrington de Gonzalez, Amy; Beland, Frederick A.; Browne, Patience; Demers, Paul A; Lachenmeier, Dirk W; Bahadori, Tina; Barupal, Dinesh K.; Belpoggi, Fiorella; Comba, Pietro; Dai, Min (June 2019). "Advisory Group recommendations on priorities for the IARC Monographs". The Lancet Oncology. 20 (6): 763–764. doi:10.1016/S1470-2045(19)30246-3. PMID 31005580. S2CID 128350881.
  2. Daniels, Robert D; Kubale, Travis L; Yiin, James H; Dahm, Matthew M; Hales, Thomas R; Baris, Dalsu; Zahm, Shelia H; Beaumont, James J; Waters, Kathleen M; Pinkerton, Lynne E (June 2014). "Mortality and cancer incidence in a pooled cohort of US firefighters from San Francisco, Chicago and Philadelphia (1950–2009)". Occupational and Environmental Medicine. 71 (6): 388–397. doi:10.1136/oemed-2013-101662. ISSN 1351-0711. PMC 4499779. PMID 24142974.
  3. LeMasters, Grace K.; Genaidy, Ash M.; Succop, Paul; Deddens, James; Sobeih, Tarek; Barriera-Viruet, Heriberto; Dunning, Kari; Lockey, James (November 2006). "Cancer Risk Among Firefighters: A Review and Meta-analysis of 32 Studies". Journal of Occupational and Environmental Medicine. 48 (11): 1189–1202. doi:10.1097/01.jom.0000246229.68697.90. ISSN 1076-2752. PMID 17099456. S2CID 1659335.
  4. Painting, Firefighting, and Shiftwork. International Agency for Research on Cancer. 2010. ISBN 9789283215981. OCLC 1066415095.{{cite book}}: CS1 maint: others (link)
  5. Laroche, Elena; L’Espérance, Sylvain (March 3, 2021). "Cancer Incidence and Mortality among Firefighters: An Overview of Epidemiologic Systematic Reviews". International Journal of Environmental Research and Public Health. 18 (5): 2519. doi:10.3390/ijerph18052519. ISSN 1660-4601. PMC 7967542. PMID 33802629.
  6. Hwang, Jooyeon; Xu, Chao; Agnew, Robert J.; Clifton, Shari; Malone, Tara R. (January 2021). "Health Risks of Structural Firefighters from Exposure to Polycyclic Aromatic Hydrocarbons: A Systematic Review and Meta-Analysis". International Journal of Environmental Research and Public Health. 18 (8): 4209. doi:10.3390/ijerph18084209. PMC 8071552. PMID 33921138.
  7. Jalilian, Hamed; Ziaei, Mansour; Weiderpass, Elisabete; Rueegg, Corina Silvia; Khosravi, Yahya; Kjaerheim, Kristina (November 15, 2019). "Cancer incidence and mortality among firefighters". International Journal of Cancer. 145 (10): 2639–2646. doi:10.1002/ijc.32199. ISSN 0020-7136. PMID 30737784. S2CID 73451966.
  8. Soteriades, Elpidoforos S; Kim, Jaeyoung; Christophi, Costas A; Kales, Stefanos N (November 1, 2019). "Cancer Incidence and Mortality in Firefighters: A State-of-the-Art Review and Meta-َAnalysis". Asian Pacific Journal of Cancer Prevention. 20 (11): 3221–3231. doi:10.31557/APJCP.2019.20.11.3221. ISSN 2476-762X. PMC 7063017. PMID 31759344.
  9. Casjens, Swaantje; Brüning, Thomas; Taeger, Dirk (October 2020). "Cancer risks of firefighters: a systematic review and meta-analysis of secular trends and region-specific differences". International Archives of Occupational and Environmental Health. 93 (7): 839–852. doi:10.1007/s00420-020-01539-0. ISSN 0340-0131. PMC 7452930. PMID 32306177.
  10. Lee, David J.; Koru‐Sengul, Tulay; Hernandez, Monique N.; Caban‐Martinez, Alberto J.; McClure, Laura A.; Mackinnon, Jill A.; Kobetz, Erin N. (April 2020). "Cancer risk among career male and female Florida firefighters: Evidence from the Florida Firefighter Cancer Registry (1981‐2014)". American Journal of Industrial Medicine. 63 (4): 285–299. doi:10.1002/ajim.23086. ISSN 0271-3586. PMID 31930542. S2CID 210191181.
  11. Pinkerton, Lynne; Bertke, Stephen J; Yiin, James; Dahm, Matthew; Kubale, Travis; Hales, Thomas; Purdue, Mark; Beaumont, James J; Daniels, Robert (February 2020). "Mortality in a cohort of US firefighters from San Francisco, Chicago and Philadelphia: an update". Occupational and Environmental Medicine. 77 (2): 84–93. doi:10.1136/oemed-2019-105962. ISSN 1351-0711. PMID 31896615. S2CID 209677270.
  12. Ahn, Yeon-Soon; Jeong, Kyoung-Sook; Kim, Kyoo-Sang (September 2012). "Cancer morbidity of professional emergency responders in Korea". American Journal of Industrial Medicine. 55 (9): 768–778. doi:10.1002/ajim.22068. PMID 22628010. S2CID 41791288.
  13. Amadeo, Brice; Marchand, Jean-Luc; Moisan, Frédéric; Donnadieu, Stéphane; Coureau, Gaëlle; Mathoulin-Pélissier, Simone; Lembeye, Christian; Imbernon, Ellen; Brochard, Patrick (2015). "French firefighter mortality: Analysis over a 30-year period". American Journal of Industrial Medicine. 58 (4): 437–443. doi:10.1002/ajim.22434. ISSN 1097-0274. PMID 25708859.
  14. Glass, D. C.; Pircher, S.; Monaco, A. Del; Hoorn, S. Vander; Sim, M. R. (November 1, 2016). "Mortality and cancer incidence in a cohort of male paid Australian firefighters". Occupational and Environmental Medicine. 73 (11): 761–771. doi:10.1136/oemed-2015-103467. ISSN 1351-0711. PMID 27456156. S2CID 43114491.
  15. Glass, Deborah C; Del Monaco, Anthony; Pircher, Sabine; Vander Hoorn, Stephen; Sim, Malcolm R (September 2017). "Mortality and cancer incidence among male volunteer Australian firefighters". Occupational and Environmental Medicine. 74 (9): 628–638. doi:10.1136/oemed-2016-104088. ISSN 1351-0711. PMID 28391245. S2CID 32602571.
  16. Glass, Deborah Catherine; Del Monaco, Anthony; Pircher, Sabine; Vander Hoorn, Stephen; Sim, Malcolm Ross (April 2019). "Mortality and cancer incidence among female Australian firefighters". Occupational and Environmental Medicine. 76 (4): 215–221. doi:10.1136/oemed-2018-105336. ISSN 1470-7926. PMID 30674605. S2CID 59226066.
  17. Harris, M. Anne; Kirkham, Tracy L.; MacLeod, Jill S.; Tjepkema, Michael; Peters, Paul A.; Demers, Paul A. (October 2018). "Surveillance of cancer risks for firefighters, police, and armed forces among men in a Canadian census cohort". American Journal of Industrial Medicine. 61 (10): 815–823. doi:10.1002/ajim.22891. PMID 30073696. S2CID 51905238.
  18. Kirstine Ugelvig Petersen, Kajsa; Pedersen, Julie Elbaek; Bonde, Jens Peter; Ebbehoej, Niels Erik; Hansen, Johnni (April 2018). "Long-term follow-up for cancer incidence in a cohort of Danish firefighters". Occupational and Environmental Medicine. 75 (4): 263–269. doi:10.1136/oemed-2017-104660. ISSN 1351-0711. PMID 29055884. S2CID 4395029.
  19. Petersen, Kajsa Ugelvig; Pedersen, Julie Elbæk; Bonde, Jens Peter; Ebbehøj, Niels Erik; Hansen, Johnni (August 2018). "Mortality in a cohort of Danish firefighters; 1970–2014". International Archives of Occupational and Environmental Health. 91 (6): 759–766. doi:10.1007/s00420-018-1323-6. ISSN 0340-0131. PMID 29808435. S2CID 44168738.
  20. Pukkala, Eero; Martinsen, Jan Ivar; Weiderpass, Elisabete; Kjaerheim, Kristina; Lynge, Elsebeth; Tryggvadottir, Laufey; Sparén, Pär; Demers, Paul A (June 2014). "Cancer incidence among firefighters: 45 years of follow-up in five Nordic countries". Occupational and Environmental Medicine. 71 (6): 398–404. doi:10.1136/oemed-2013-101803. ISSN 1351-0711. PMID 24510539. S2CID 24392558.
  21. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2010). "Painting, firefighting, and shiftwork". IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 98: 9–764. ISSN 1017-1606. PMC 4781497. PMID 21381544.
  22. J. JANKOVIC, W. JONES, J. BURKHART, G. NOONAN (1991). "Environmental study of firefighters". Annals of Occupational Hygiene. 35 (6): 581–602. doi:10.1093/annhyg/35.6.581. PMID 1768008.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  23. Bolstad-Johnson, Dawn M.; Burgess, Jefferey L.; Crutchfield, Clifton D.; Storment, Steve; Gerkin, Richard; Wilson, Jeffrey R. (September 2000). "Characterization of Firefighter Exposures During Fire Overhaul". AIHAJ - American Industrial Hygiene Association. 61 (5): 636–641. doi:10.1080/15298660008984572. ISSN 1529-8663. PMID 11071414.
  24. Austin, C. C.; Wang, D.; Ecobichon, D. J.; Dussault, G. (July 15, 2001). "Characterization of Volatile Organic Compounds in Smoke at Municipal Structural Fires". Journal of Toxicology and Environmental Health, Part A. 63 (6): 437–458. doi:10.1080/152873901300343470. ISSN 1528-7394. PMID 11482799. S2CID 36263955.
  25. Fent, Kenneth W.; Alexander, Barbara; Roberts, Jennifer; Robertson, Shirley; Toennis, Christine; Sammons, Deborah; Bertke, Stephen; Kerber, Steve; Smith, Denise; Horn, Gavin (October 3, 2017). "Contamination of firefighter personal protective equipment and skin and the effectiveness of decontamination procedures". Journal of Occupational and Environmental Hygiene. 14 (10): 801–814. doi:10.1080/15459624.2017.1334904. ISSN 1545-9624. PMID 28636458. S2CID 44916370.
  26. Mayer, Alexander C.; Fent, Kenneth W.; Bertke, Stephen; Horn, Gavin P.; Smith, Denise L.; Kerber, Steve; La Guardia, Mark J. (February 1, 2019). "Firefighter hood contamination: Efficiency of laundering to remove PAHs and FRs". Journal of Occupational and Environmental Hygiene. 16 (2): 129–140. doi:10.1080/15459624.2018.1540877. ISSN 1545-9624. PMC 8647047. PMID 30427284.
  27. Beitel, Shawn C.; Flahr, Leanne M.; Hoppe-Jones, Christiane; Burgess, Jefferey L.; Littau, Sally R.; Gulotta, John; Moore, Paul; Wallentine, Darin; Snyder, Shane A. (February 1, 2020). "Assessment of the toxicity of firefighter exposures using the PAH CALUX bioassay". Environment International. 135: 105207. doi:10.1016/j.envint.2019.105207. ISSN 0160-4120. PMID 31812113. S2CID 208870627.
  28. Fent, Kenneth W.; Toennis, Christine; Sammons, Deborah; Robertson, Shirley; Bertke, Stephen; Calafat, Antonia M.; Pleil, Joachim D.; Wallace, M. Ariel Geer; Kerber, Steve; Smith, Denise; Horn, Gavin P. (March 2020). "Firefighters' absorption of PAHs and VOCs during controlled residential fires by job assignment and fire attack tactic". Journal of Exposure Science & Environmental Epidemiology. 30 (2): 338–349. doi:10.1038/s41370-019-0145-2. ISSN 1559-0631. PMC 7323473. PMID 31175324.
  29. "IARC Monographs Volume 124: Night Shift Work – IARC". www.iarc.who.int. Retrieved September 1, 2022.
  30. Demers, Paul A; DeMarini, David M; Fent, Kenneth W; Glass, Deborah C; Hansen, Johnni; Adetona, Olorunfemi; Andersen, Maria HG; Freeman, Laura E Beane; Caban-Martinez, Alberto J; Daniels, Robert D; Driscoll, Timothy R (July 1, 2022). "Carcinogenicity of occupational exposure as a firefighter". The Lancet Oncology. 23 (8): 985–986. doi:10.1016/S1470-2045(22)00390-4. ISSN 1470-2045. PMID 35780778. S2CID 250227232.
  31. "Firefighters : Occupational Outlook Handbook: : U.S. Bureau of Labor Statistics". www.bls.gov. Retrieved February 1, 2022.
  32. Navarro, Kathleen M.; Kleinman, Michael T.; Mackay, Chris E.; Reinhardt, Timothy E.; Balmes, John R.; Broyles, George A.; Ottmar, Roger D.; Naher, Luke P.; Domitrovich, Joseph W. (June 2019). "Wildland firefighter smoke exposure and risk of lung cancer and cardiovascular disease mortality". Environmental Research. 173: 462–468. Bibcode:2019ER....173..462N. doi:10.1016/j.envres.2019.03.060. PMID 30981117. S2CID 108987257.
  33. Glass, D. C.; Del Monaco, A.; Pircher, S.; Vander Hoorn, S.; Sim, M. R. (October 2016). "Mortality and cancer incidence at a fire training college". Occupational Medicine (Oxford, England). 66 (7): 536–542. doi:10.1093/occmed/kqw079. ISSN 1471-8405. PMID 27371948.
  34. Abreu, Ana; Costa, Carla; Pinho e Silva, Susana; Morais, Simone; do Carmo Pereira, Maria; Fernandes, Adília; Moraes de Andrade, Vanessa; Teixeira, João Paulo; Costa, Solange (August 3, 2017). "Wood smoke exposure of Portuguese wildland firefighters: DNA and oxidative damage evaluation". Journal of Toxicology and Environmental Health, Part A. 80 (13–15): 596–604. doi:10.1080/15287394.2017.1286896. hdl:10216/111908. ISSN 1528-7394. PMID 28524757. S2CID 205867973.
  35. Adetona, Olorunfemi; Simpson, Christopher D; Li, Zheng; Sjodin, Andreas; Calafat, Antonia M; Naeher, Luke P (November 11, 2015). "Hydroxylated polycyclic aromatic hydrocarbons as biomarkers of exposure to wood smoke in wildland firefighters". Journal of Exposure Science & Environmental Epidemiology. 27 (1): 78–83. doi:10.1038/jes.2015.75. ISSN 1559-0631. PMC 5140750. PMID 26555473.
  36. Andersen, Maria Helena Guerra; Saber, Anne Thoustrup; Clausen, Per Axel; Pedersen, Julie Elbæk; Løhr, Mille; Kermanizadeh, Ali; Loft, Steffen; Ebbehøj, Niels; Hansen, Åse Marie; Pedersen, Peter Bøgh; Koponen, Ismo Kalevi (February 24, 2018). "Association between polycyclic aromatic hydrocarbon exposure and peripheral blood mononuclear cell DNA damage in human volunteers during fire extinction exercises". Mutagenesis. 33 (1): 105–115. doi:10.1093/mutage/gex021. ISSN 0267-8357. PMID 29045708.
  37. Keir, Jennifer L. A.; Akhtar, Umme S.; Matschke, David M. J.; Kirkham, Tracy L.; Chan, Hing Man; Ayotte, Pierre; White, Paul A.; Blais, Jules M. (November 7, 2017). "Elevated Exposures to Polycyclic Aromatic Hydrocarbons and Other Organic Mutagens in Ottawa Firefighters Participating in Emergency, On-Shift Fire Suppression". Environmental Science & Technology. 51 (21): 12745–12755. Bibcode:2017EnST...5112745K. doi:10.1021/acs.est.7b02850. ISSN 0013-936X. PMID 29043785.
  38. Hoppe-Jones, C.; Beitel, S.; Burgess, J. L.; Snyder, S.; Flahr, L.; Griffin, S.; Littau, S.; Jeong, K. S.; Zhou, J.; Gulotta, J.; Moore, P. (April 1, 2018). "515 Use of urinary biomarkers and bioassays to evaluate chemical exposure and activation of cancer pathways in firefighters". Occupational and Environmental Medicine. 75 (Suppl 2): A412–A413. doi:10.1136/oemed-2018-ICOHabstracts.1178. ISSN 1351-0711. S2CID 80490930.
  39. Jeong, Kyoung Sook; Zhou, Jin; Griffin, Stephanie C.; Jacobs, Elizabeth T.; Dearmon-Moore, Devi; Zhai, Jing; Littau, Sally R.; Gulotta, John; Moore, Paul; Peate, Wayne F.; Richt, Crystal M. (May 2018). "MicroRNA Changes in Firefighters". Journal of Occupational & Environmental Medicine. 60 (5): 469–474. doi:10.1097/JOM.0000000000001307. ISSN 1076-2752. PMC 5959213. PMID 29465512.
  40. Oliveira, M.; Delerue-Matos, C.; Morais, S.; Slezakova, K.; Pereira, M.C.; Fernandes, A.; Costa, S.; Teixeira, J.P. (March 14, 2018), "Levels of urinary biomarkers of exposure and potential genotoxic risks in firefighters", Occupational Safety and Hygiene VI, CRC Press, pp. 267–271, doi:10.1201/9781351008884-47, ISBN 978-1-351-00888-4, retrieved February 1, 2022
  41. Daniels, Robert D; Kubale, Travis L; Yiin, James H; Dahm, Matthew M; Hales, Thomas R; Baris, Dalsu; Zahm, Shelia H; Beaumont, James J; Waters, Kathleen M; Pinkerton, Lynne E (June 2014). "Mortality and cancer incidence in a pooled cohort of US firefighters from San Francisco, Chicago and Philadelphia (1950–2009)". Occupational and Environmental Medicine. 71 (6): 388–397. doi:10.1136/oemed-2013-101662. ISSN 1351-0711. PMC 4499779. PMID 24142974.
  42. Tsai, Rebecca J.; Luckhaupt, Sara E.; Schumacher, Pam; Cress, Rosemary D.; Deapen, Dennis M.; Calvert, Geoffrey M. (May 6, 2015). "Risk of cancer among firefighters in California, 1988-2007". American Journal of Industrial Medicine. 58 (7): 715–729. doi:10.1002/ajim.22466. ISSN 0271-3586. PMC 4527530. PMID 25943908.
  43. Lee, David J.; Koru-Sengul, Tulay; Hernandez, Monique N.; Caban-Martinez, Alberto J.; McClure, Laura A.; Mackinnon, Jill A.; Kobetz, Erin N. (April 2020). "Cancer risk among career male and female Florida firefighters: Evidence from the Florida Firefighter Cancer Registry (1981-2014)". American Journal of Industrial Medicine. 63 (4): 285–299. doi:10.1002/ajim.23086. ISSN 1097-0274. PMID 31930542. S2CID 210191181.
  44. Ma, Fangchao; Fleming, Lora E.; Lee, David J.; Trapido, Edward; Gerace, Terence A. (September 2006). "Cancer incidence in Florida professional firefighters, 1981 to 1999". Journal of Occupational and Environmental Medicine. 48 (9): 883–888. doi:10.1097/01.jom.0000235862.12518.04. ISSN 1076-2752. PMID 16966954. S2CID 45179842.
  45. "Employed persons by detailed occupation, sex, race, and Hispanic or Latino ethnicity". www.bls.gov. Retrieved February 1, 2022.
  46. "NFPA report - U.S. fire department profile". www.nfpa.org. 2018. Retrieved February 1, 2022.
  47. Freeman, MaryBeth B.; Pollack, Lori A.; Rees, Judy R.; Johnson, Christopher J.; Rycroft, Randi K.; Rousseau, David L.; Hsieh, Mei-Chin; enhancement of NPCR for comparative effectiveness research team (August 2017). "Capture and coding of industry and occupation measures: Findings from eight National Program of Cancer Registries states". American Journal of Industrial Medicine. 60 (8): 689–695. doi:10.1002/ajim.22739. ISSN 1097-0274. PMC 5769461. PMID 28692191.
  48. Silver, Sharon R.; Tsai, Rebecca J.; Morris, Cyllene R.; Boiano, James M.; Ju, Jun; Scocozza, Marilyn S.; Calvert, Geoffrey M. (June 2018). "Codability of industry and occupation information from cancer registry records: Differences by patient demographics, casefinding source, payor, and cancer type". American Journal of Industrial Medicine. 61 (6): 524–532. doi:10.1002/ajim.22840. ISSN 1097-0274. PMID 29574892. S2CID 4308062.
  49. McClure, Laura A.; Koru-Sengul, Tulay; Hernandez, Monique N.; Mackinnon, Jill A.; Solle, Natasha Schaefer; Caban-Martinez, Alberto J.; Lee, David J.; Kobetz, Erin (April 30, 2019). "Availability and accuracy of occupation in cancer registry data among Florida firefighters". PLOS ONE. 14 (4): e0215867. Bibcode:2019PLoSO..1415867M. doi:10.1371/journal.pone.0215867. ISSN 1932-6203. PMC 6490882. PMID 31039169.
  50. Daniels, Robert D.; Bertke, Stephen; Dahm, Matthew M.; Yiin, James H.; Kubale, Travis L.; Hales, Thomas R.; Baris, Dalsu; Zahm, Shelia H.; Beaumont, James J.; Waters, Kathleen M.; Pinkerton, Lynne E. (October 2015). "Exposure-response relationships for select cancer and non-cancer health outcomes in a cohort of U.S. firefighters from San Francisco, Chicago and Philadelphia (1950-2009)". Occupational and Environmental Medicine. 72 (10): 699–706. doi:10.1136/oemed-2014-102671. ISSN 1470-7926. PMC 4558385. PMID 25673342.
  51. Humans, IARC Working Group on the Evaluation of Carcinogenic Risk to (2012). Personal Habits and Indoor Combustions. [Place of publication not identified]: International Agency for Research on Cancer. ISBN 978-92-832-0137-3. OCLC 1021252135.
  52. Thun, Michael; Linet, Martha S.; Cerhan, James R.; Haiman, Christopher A.; Schottenfeld, David, eds. (December 21, 2017). Cancer Epidemiology and Prevention. Vol. 1. Oxford University Press. doi:10.1093/oso/9780190238667.001.0001. ISBN 978-0-19-023866-7.
  53. Collins, Chris (July 7, 2018). "H.R.931 - 115th Congress (2017-2018): Firefighter Cancer Registry Act of 2018". www.congress.gov. Archived from the original on September 20, 2022. Retrieved September 30, 2022.
  54. Menendez, Robert (April 25, 2018). "S.382 - 115th Congress (2017-2018): Firefighter Cancer Registry Act of 2018". www.congress.gov. Archived from the original on September 20, 2022. Retrieved September 30, 2022.
  55. "Bill would establish firefighter cancer registry". www.safetyandhealthmagazine.com. Retrieved March 17, 2022.
  56. "US Launches First National Firefighter Cancer Registry". Mesothelioma Center - Vital Services for Cancer Patients & Families. Archived from the original on August 5, 2021. Retrieved September 27, 2022.
  57. One Hundred Fifteenth Congress of the United States of America (PDF). Archived (PDF) from the original on March 24, 2022.
  58. Otis, Ginger Adams. "Chuck Schumer wants Congress to create voluntary health registry that tracks firefighters with cancer". nydailynews.com. Archived from the original on March 17, 2022. Retrieved March 17, 2022.
  59. "Breaking News: House Unanimously Approves Firefighter Cancer Registry Act – Virginia Department of Fire Programs". www.vafire.com. Archived from the original on June 29, 2022. Retrieved September 30, 2022.
  60. "H.R. 931 Archives". Congressional Fire Services Institute. Archived from the original on November 26, 2022. Retrieved September 30, 2022.
  61. "Bipartisan Firefighter Cancer Registry Act Signed into Law". U.S. Senator Amy Klobuchar. Archived from the original on September 20, 2022. Retrieved September 30, 2022.
  62. "Firefighter Cancer Registry Act of 2018 (2018 - H.R. 931)". GovTrack.us. Retrieved May 9, 2022.
  63. "S. 382, Firefighter Cancer Registry Act of 2018 | Congressional Budget Office". www.cbo.gov. June 12, 2018. Archived from the original on May 19, 2022. Retrieved September 30, 2022.
  64. "H.R. 931, FIREFIGHTER CANCER REGISTRY ACT". RPC. Archived from the original on December 23, 2018.
  65. "National Firefighter Registry Subcommittee (NFRS)". U.S. National Institute for Occupational Safety and Health. September 6, 2022. Retrieved September 15, 2022.
  66. NFFF (June 8, 2021). "National Firefighter Registry Updates". Everyone Goes Home. Archived from the original on September 20, 2021. Retrieved September 30, 2022.
  67. "The National Firefighter Registry: An update on the plan to track firefighter cancer". FireRescue1. Archived from the original on April 7, 2022. Retrieved September 30, 2022.
  68. Fent, Kenneth W.; Siegel, Miriam; Mayer, Alexander; Wilkinson, Andrea; Raudabaugh, Jill (October 16, 2020). "National Firefighter Registry (NFR) Draft Protocol" (PDF). U.S. National Institute for Occupational Safety and Heath. Retrieved September 14, 2022.
  69. "National Firefighter Registry". IAFF. Archived from the original on January 11, 2022. Retrieved September 30, 2022.
  70. "National Firefighter Registry - FAQ". U.S. National Institute for Occupational Safety and Health. September 6, 2022. Retrieved September 15, 2022.
  71. White, Mary C.; Babcock, Frances; Hayes, Nikki S.; Mariotto, Angela B.; Wong, Faye L.; Kohler, Betsy A.; Weir, Hannah K. (December 15, 2017). "The history and use of cancer registry data by public health cancer control programs in the United States". Cancer. 123 (Suppl 24): 4969–4976. doi:10.1002/cncr.30905. ISSN 1097-0142. PMC 5846186. PMID 29205307.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.