2022 Indianapolis Colts–Minnesota Vikings game

Despite allowing the Colts to drive down to the 1-yard line on the opening possession, the Vikings were able to push them back to the 8-yard line, forcing a 26-yard field goal from former Viking Chase McLaughlin. On the ensuing drive, the Vikings were forced to punt, but Ryan Wright's kick was blocked by Ifeadi Odenigbo, another former Viking, and returned 24 yards for a touchdown by JoJo Domann. Dalvin Cook took the opening play of the Vikings' next possession 40 yards into Colts territory, but fumbled on the next play, allowing the Colts to capitalize by capping a 66-yard drive with a 1-yard touchdown run from Deon Jackson. On the Vikings' next drive, they were stopped on 3rd-and-1 and attempted to go for it on 4th down, only to be stopped again, giving the Colts the ball in Vikings territory.

As the game entered the second quarter, the Vikings' defense stood firm, forcing the Colts to kick a field goal. The Vikings were faced with another 4th-and-1 and set up to punt, only for Wright to toss the ball in the direction of Jalen Nailor; however, it fell incomplete and the Vikings turned the ball over on downs again, allowing the Colts to kick another field goal, this time from 49 yards. After another Vikings' punt, on a 3rd and 10 play, Matt Ryan threw a pass to Michael Pittman Jr. who was grabbed just past the line of scrimmage by Vikings cornerback Chandon Sullivan. Pittman, trying to fight for yards on 3rd down, was hit by Vikings linebacker Brian Asamoah II while being tackled which caused Pittman to fumble and the ball was picked up by Sullivan and returned for a subsequent touchdown. However, the referees had signaled the play was over before Pittman fumbled, saying that forward progress was stopped; taking away a potential touchdown from the Vikings. The two teams then exchanged punts before Vikings quarterback Kirk Cousins threw an interception deep in his own territory that Julian Blackmon returned 17 yards for a touchdown. The Vikings thought they had managed to ignite their offense on the next possession, but a 40-yard completion to K. J. Osborn was overturned after the Colts challenged the play. The Vikings eventually had to punt, and with four minutes left in the half, the Colts drove the ball downfield and kicked a 27-yard field goal to go into the break with a 33–0 lead.

To start the second half, the Vikings lost yardage and were again forced to punt; however, they were able to force the Colts into their second punt of the game on the following drive. A big pass from Cousins to Osborn moved the Vikings 63 yards downfield on their next possession, putting them inside the Colts' 5-yard line; after a short gain by Cook, Cousins found Osborn in the end zone for the Vikings' first points of the game. The defense then made a stop as the Colts entered Vikings territory, limiting them to a 52-yard field goal, before the Vikings offense marched downfield to score another touchdown via a 1-yard run from fullback C. J. Ham. They then closed out the third quarter by forcing the Colts into another punt.

They opened the fourth quarter with a 20-yard completion from Cousins to Justin Jefferson, and an unnecessary roughness penalty on Rodney Thomas II added another 15 yards. Another Jefferson catch for 17 yards got the Vikings into the red zone, and the drive was capped by a third Jefferson catch for an 8-yard touchdown, reducing the deficit to 15 points. The Colts punted again on the next possession, and Jalen Reagor returned the kick 51 yards to put the Vikings on the verge of the red zone again, only for the play to be called back for a facemask penalty against Vikings cornerback Kris Boyd. The Vikings made their way downfield, helped by another unnecessary roughness penalty for a hit on Jefferson by Stephon Gilmore, only for Cousins to throw another interception when targeting Reagor on a deep route that the receiver appeared to give up on. The Colts started on their own 2-yard line, but could not capitalize on the turnover as the Vikings forced them to punt once again, and Reagor made a fair catch at midfield. Completions to Adam Thielen (his first target of the game) and Osborn, followed by a pass interference penalty in the end zone, got the Vikings down to the Colts 1-yard line, and they scored a touchdown on the third attempt, when Cousins found Thielen in the end zone. The Colts managed a first down on their next possession, but on the very next play, Jackson fumbled, and Chandon Sullivan recovered the ball and returned it for what he thought was a touchdown, only for the officials to rule Jackson to have been down by contact; Sullivan's protestations earned him a 15-yard penalty for unsportsmanlike conduct. On review, the play was confirmed as a fumble, giving the Vikings the ball, but because the officials had whistled, they could not award the touchdown. The second time in the game a potential defensive touchdown was taken away from Chandon Sullivan and the Vikings. Following the penalty, the Vikings started just inside their own half, but despite Jefferson picking up a pair of 7-yard catches, the drive stalled. On 4th-and-15, Cousins attempted to run for the first down, but he was tripped and the Vikings turned the ball over on downs for a third time with 2:52 left in the quarter. The Colts moved into Vikings territory, but faced with a 4th-and-1 on the Vikings' 36-yard line, Matt Ryan was stopped short on a quarterback sneak. The Vikings used all three of their timeouts during the Colts' drive, but on the first play of the following possession, Dalvin Cook took a screen pass 64 yards downfield for a touchdown. The Vikings attempted a two-point conversion, and Cousins found T. J. Hockenson in the end zone, tying the game with 2:15 left to play. The teams then traded punts, sending the game to overtime.

The Vikings won the toss ahead of the extra period and elected to receive the ball, but their opening drive stalled following a Cousins sack and an offensive holding penalty against guard Ezra Cleveland. A 14-yard catch by Hockenson put the Vikings on the verge of Greg Joseph's field goal range, but they declined the 57-yard attempt and punted instead. The defense then forced the Colts into a punt following a short drive, leaving the Vikings on their own 18-yard line. After a 6-yard run by Cook, Cousins completed passes to Osborn, Thielen and Jefferson to get the Vikings down to the Colts' 27-yard line with 20 seconds left to play, and a delay of game penalty against Odenigbo moved them 5 yards closer to the end zone. That presented Joseph with the opportunity for a 40-yard, game-winning field goal. Despite the Colts using a timeout in an attempt to ice the kicker, Joseph's kick was successful, giving the Vikings a 39–36 win and completing the biggest comeback in NFL history.