7-Methylxanthine

7-Methylxanthine
Clinical data
Other names	7-MX; 7-Methylxanthin; Heteroxanthin; Heteroxanthine; NSC-7861
Identifiers
	IUPAC name 7-methyl-3H-purine-2,6-dione;
CAS Number	552-62-5;
PubChem CID	68374;
ChemSpider	61660;
UNII	E9M81NJM6G;
KEGG	C16353;
ChEBI	CHEBI:48991;
ChEMBL	ChEMBL321248;
Chemical and physical data
Formula	C6H6N4O2
Molar mass	166.140 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1C=NC2=C1C(=O)NC(=O)N2;
	InChI InChI=1S/C6H6N4O2/c1-10-2-7-4-3(10)5(11)9-6(12)8-4/h2H,1H3,(H2,8,9,11,12); Key:PFWLFWPASULGAN-UHFFFAOYSA-N;

7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine).[1][2] It is a non-selective antagonist of the adenosine receptors.[1][2] The compound may slow the progression of myopia (nearsightedness).[1][2] It is under investigation for this purpose in children with myopia.[1][2]

References

"7-Methylxanthine". Inxight Drugs. Retrieved 24 August 2022.
Singh H, Singh H, Latief U, Tung GK, Shahtaghi NR, Sahajpal NS, et al. (August 2022). "Myopia, its prevalence, current therapeutic strategy and recent developments: A Review". Indian Journal of Ophthalmology. 70 (8): 2788–2799. doi:10.4103/ijo.IJO_2415_21. PMID 35918918. S2CID 251281523.

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