Deborah Dunn-Walters
Deborah Kay Dunn-Walters FRSB (born September 1963) is a British immunologist who is Professor of Immunology at the University of Surrey. Her research considers B-cell development in disease. During the COVID-19 pandemic, Dunn-Walters focussed on the development of single cell analyses of the immunological responses to SARS-CoV-2. She is a member of the Scientific Advisory Group for Emergencies, and provided the government with scientific advice during the pandemic.
Deborah Dunn-Walters | |
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Born | 1963 (age 59–60) |
Alma mater | University of Surrey |
Scientific career | |
Institutions | University of Surrey King's College London |
Thesis | Studies on the human glutathione peroxidase gene and related DNA sequences (1990) |
Early life and education
Dunn-Walters worked toward her doctorate at the University of Surrey. Her research considered the glutathione peroxidase gene.[1]
Research and career
Dunn-Walters studies B cell development during disease, and how the immune system changes during ageing.[2] She has developed new characterisation techniques to understand immune responses, including single-cell approaches. She is part of the CARINA (Catalyst Reducing Immune Ageing) Network, a collective which looks to understand how ageing impacts the immune system.[3]
During the COVID-19 pandemic, Dunn-Walters served as a scientific advisor to the Government of the United Kingdom. She was a member of the Scientific Advisory Group for Emergencies (SAGE), and Chair of the British Society for Immunology COVID-19 Taskforce.[4] Working with the Joint Committee on Vaccination and Immunisation (JCVI), Dunn-Walters recommended all who were able to have the COVID-19 vaccine.[4]
Selected publications
- Kate L Gibson; Yu-Chang Wu; Yvonne Barnett; et al. (5 November 2008). "B-cell diversity decreases in old age and is correlated with poor health status". Aging Cell. 8 (1): 18–25. doi:10.1111/J.1474-9726.2008.00443.X. ISSN 1474-9718. PMC 2667647. PMID 18986373. Wikidata Q37155196.
- Yu-Chang Wu; David Kipling; Hui Sun Leong; Victoria Martin; Alexander A Ademokun; Deborah K Dunn-Walters (10 May 2010). "High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations". Blood. 116 (7): 1070–1078. doi:10.1182/BLOOD-2010-03-275859. ISSN 0006-4971. PMC 2938129. PMID 20457872. Wikidata Q30496575.
- Dunn-Walters DK; Isaacson PG; Spencer J (1 August 1995). "Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells". Journal of Experimental Medicine. 182 (2): 559–566. doi:10.1084/JEM.182.2.559. ISSN 0022-1007. PMC 2192131. PMID 7629512. Wikidata Q36365247.
References
- "Studies on the human glutathione peroxidase gene and related DNA sequences | WorldCat.org". www.worldcat.org. Retrieved 1 January 2023.
- "Prof Deborah Dunn-Walters | University of Surrey". www.surrey.ac.uk. Retrieved 1 January 2023.
- "New network to boost understanding of immune system and ageing | University of Surrey". www.surrey.ac.uk. Retrieved 1 January 2023.
- "expert reaction to JCVI advice on COVID-19 vaccines for the autumn booster programme | Science Media Centre". Retrieved 1 January 2023.