Hexethal

Hexethal (Ortal) is a barbiturate derivative invented in the 1940s. It has sedative, anxiolytic, muscle relaxant, and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine. [1]

Hexethal
Clinical data
Other namesSodium 5-ethyl-5-hexylbarbiturate, Ortal, Hebaral
ATC code
  • none
Legal status
Legal status
Identifiers
  • sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H19N2NaO3
Molar mass262.285 g·mol−1
3D model (JSmol)
  • [Na+].O=C1/N=C(/[O-])NC(=O)C1(CCCCCC)CC
  • InChI=1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 checkY
  • Key:HXUAXLUDTCGASZ-UHFFFAOYSA-M checkY
  (verify)

Hexethal is considered similar in effects to pentobarbital, with a very fast onset of action but short duration of effects.

References
  1. Butler TC (October 1950). "The rate of penetration of barbituric acid derivatives into the brain". The Journal of Pharmacology and Experimental Therapeutics. 100 (2): 219–26. PMID 14784958.
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