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Aminoglycosides
From WikEM
Background
- Used (alone or with beta-lactam) to treat serious infections due to gram-negative bacilli, e.g.:
- Ill patient with pyelonephritis
- Meningitis (due to pseudomonas, acinetobacter)
- Peritoneal dialysis-associated peritonitis
- Bacterial endocarditis
- Used +/- beta-lactam
- Nephro and oto toxic. Risk of neuromuscular blockade.
- Can precipitate crisis in patients with myasthenia gravis
- Include gentamicin and tobramycin
See Also
References
Goodman & Gilman's Pharmacology
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