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Ulipristal
From WikEM
Contents
Administration
- Type: Contraceptive
- Dosage Forms:
- Routes of Administration: Oral
- Common Trade Names: ella
Adult Dosing
- 30 mg PO once as soon as possible within 120 hours of unprotected intercourse or suspected contraceptive failure
Pediatric Dosing
- Postpubertal adolescents: see above
Special Populations
- Pregnancy Rating: X
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing:
- Hepatic dosing:
Contraindications
- Allergy to class/drug
- Pregnancy
Adverse Reactions
Serious
Common
- Nausea, abdominal pain
- Headache
Pharmacology
- Half-life: 26-38h
- Metabolism: Hepatic via CYP3A4
- Excretion:
Mechanism of Action
- Prevents progesterone from binding to progesterone receptor, thereby inhibiting or delaying ovulation
