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Vecuronium
From WikEM
Contents
General
- Type: Neuromuscular blocker, nondepolarizing, fast
- Dosage Forms: IV
- Common Trade Names: Norcuron
Adult Dosing
- Not recommended for RSI
- 0.15mg/kg IV based on ideal body weight, can prime with 0.01mg/kg IV
Pediatric Dosing
- Not recommended for RSI
Special Populations
- Pregnancy Rating: C
- Lactation: Infant risk cannot be ruled out
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: Varies, from 30-60 minutes
- Metabolism: Hepatic
- Excretion: Renal
- Mechanism of Action: Non-depolarizing neuromuscular blocking agent. Long duration with slow onset. Competes for cholinergic receptors at the motor end-plate. Acetylcholinesterase inhibitors like those found in organophosphates antagonize this action
See Also
- Critical care quick reference
- Reversal agent: Sugammadex
References
Micromedex
Authors
Ross Donaldson, Kian Preston-Suni, Daniel Ostermayer, Neil Young, Claire
